Chía Patiño recently directed Don Giovanni for the Aspen Music Festival, Florencia en el Amazonas for Opera Tenerife, Orpheus & Eurydice for Seattle Opera, Suite Española: Exploring Iberia and Exploring the Caribbean for Houston Grand Opera, La Cenerentola and Tosca for Northern Lights Music Festival, Don Giovanni for Butler Opera Center, and her adaptation of the Magic Flute using the Andean cosmovision: La Flauta Mágica de Los Andes. Other works include Faust, La Traviata, Hansel and Gretel, Rusalka, Dido and Aeneas, Carmen, Così fan tutte, Transformations, Luisa Fernanda, Sweeney Todd, West Side Story, Spring Awakening, and Los Miserables.   

She conducted the Mariachi Vargas de Tecalitán in the opera mariachi Cruzar la Cara de la Luna, commissioned by HGO in 2009 at the Chatelêt Theater in Paris, Arizona, Phoenix, San Diego, Fort Worth, Chicago, and El Paso and the choral world premiere at the Teatro Nacional Sucre in Ecuador.