Lester Seigel's work as a conductor has been internationally noted for his choir's "seamless phrasing and sensitive blending" and "wonderfully exuberant and euphonious" sound ( Gramophone). His busy schedule of performances as a conductor and accompanist includes prestigious venues throughout the United States and abroad. As founder and conductor of the professional vocal ensemble Sursum Corda he has performed at both state and national conferences of the American Choral Directors Association, and has appeared professionally with the Alabama Symphony Orchestra under maestros Justin Brown and Carlos Izcaray. Prof. Seigel has led the BSC Concert Choir in concert at prestigious venues throughout the eastern United States and in Europe, including the choir's New York performance at Alice Tully Hall, and at Carnegie Hall as the sole choral ensemble in Ernest Bloch's "Sacred Service," with Seigel conducting the BSC forces and the New England Symphonic Ensemble. He has been re-engaged to conduct at Carnegie Hall in May 2018, leading a combined choir and the New England ensemble in Leonard Bernstein's "Chichester Psalms" and other works.

Since 1989, he has been Organist at Canterbury United Methodist Church in Mountain Brook, and its Choirmaster since 1995.

Seigel is a published composer and arranger. The audiobook version of "The Diaries of Adam and Eve" by Mark Twain, for which he composed and conducted an original score, was nominated by a Grammy Award. A selection of his published compositions are available at JW Pepper.

Seigel is also active as an organ recitalist and in chamber music. He holds the AAGO certification from the American Guild of Organists.

He has two CDs available commercially with Sursum Corda, and the Christmas recording "To You We Bring This Glad Noel" with the BSC Concert Choir is also available.