Praised as a "consummate vocal actress" (Fanfare), Michelle Areyzaga is held in high regard throughout the United States and beyond for her "appealing, expressive soprano" (New York Times).

As an orchestra soloist, Areyaga has appeared with the Chicago Symphony, Chicago Philharmonic, Buffalo Philharmonic, Minnesota Orchestra, Phoenix Symphony, Rhode Island Philharmonic, Richmond Symphony, Colorado Symphony, North Carolina Symphony, Hartford Symphony, San Antonio Symphony, Cleveland Orchestra, Toledo Symphony and Rochester Symphony.  She has also appeared at Ravinia, the Oregon Bach, Blossom, and Grant Park music festivals.

Abroad, Areyzaga has performed with the Orquesta Sinfónica de México, Orquesta Filarmónica de Montevideo, and Urugay's Orquesta Sinfónica del Sodre.  She sang in Costa Rica's first performance of Bach's B Minor Mass with the National Symphony Orchestra, John Nelson conducting; and, has appeared as soloist in Vaughan Williams' Mass in G Minor at England's York Minster Cathedral, Ely Cathedral, and St. Mary's Church in Oxford.  At Paris's L'église de la Madeleine, where she was soloist in Haydn's Lord Nelson Mass with the orchestra of London's Royal Academy of Music.

Areyzaga has sung leading roles for New York City Opera, Chicago Opera Theater, Opera Birmingham, and other regional companies which include Micaela (Carment), Cio-Cio-San (Madama Butterfly), Susanna (Le nozze di Figaro), Musetta (La bohème), Pamina (Die Zauberflöte) and Cunegonde (Dandide).

An avid chamber musician ad recitalist, she has been a repeat guest of the Chamber Music Society of Lincoln Center, the New York Festival of Song, the Avalon String Quartet, The Lincoln Trio, and the Chicago Ensemble.  She has championed Leonard Bernstein's music on numerous occasions and was named Musical Ambassador of the Ravinia Festival's Bernstein at 100 Centennial Celebration.

She has recorded for the Naxos, Proteus, 4Tay Records and the Cedille record labels.