Singing has undeniably been Nathalie Lermitte's true calling. In fact, she began her performing career at the tender age of six.

When she reached the age of 18, she simultaneously celebrated her birthday and the release of her debut album, Tu es tout ce que j'aime. Two singles from this album went on to sell over 400,000 copies. In 1995, she had the honor of opening for Michel Leeb at the Olympia, sharing the stage with Herbert Léonard.

In addition to her singing career, Nathalie Lermitte recorded numerous theme songs for television series and cartoons. In 1989, she ventured into the world of musical theater, taking on the role of Cristal in Starmania, which she performed for three years at the Théâtre Marigny in Paris and then during a national tour that culminated in Moscow and Saint Petersburg. This marked the beginning of a series of musical roles, where she often portrayed Edith Piaf.

Simultaneously, she served as a music columnist on the program Chabada, airing every Sunday at 5pm on France 3 from 2009 to 2012.

Since February 2015, Nathalie Lermitte has been captivating audiences with her portrayal of the Queen in the play La petite fille aux allumettes, a production nominated for a Molière award and directed by David Rozen.

In 2017, she joined the production of Piaf! The Show, which achieved global acclaim and success.